This page lists every known solution for the clue “Main Artery” in Crossword Challenge. Because this clue can appear in different puzzles (levels) with different required answers, we first list all the answers, then show which one appears in each puzzle below.
Main Artery Crossword Challenge Answers (All Variants)
Aorta
If more than one answer is listed, open your puzzle page below to confirm the one used there.
All Known Answers for Main Artery Clue
Puzzle 39 — - Puzzle 300 —
- Puzzle 700 —
Where This Clue Appears
Last Checked: September 12, 2025